Configuring a standalone development server that is running MOSS 2007 SP1, we wanted to point SharePoint at the local SMTP instance.
We needed to configure that SMTP instance to relay messages, but we were seeing ‘Unspecified Error’ if we tried making changes to the Access tab.
The hotfix was removed, and the settings on the Access tab changed successfully.
We then re applied the hotfix. This effectively locks us out of the Access tab again, but we can always request hotfix 950426, which looks like it was made available around the middle of August, although there is no KB article for it yet.